T K Kvien Selected Research

4-hexyloxyaniline (HOA)

4/2016	Synovitis and radiographic progression in non-erosive and erosive hand osteoarthritis: is erosive hand osteoarthritis a separate inflammatory phenotype?
8/2010	The responsiveness of joint counts, patient-reported measures and proposed composite scores in hand osteoarthritis: analyses from a placebo-controlled trial.
1/2010	Distribution of joint involvement in women with hand osteoarthritis and associations between joint counts and patient-reported outcome measures.
1/2009	Health status and perception of pain: a comparative study between female patients with hand osteoarthritis and rheumatoid arthritis.
7/2008	Efficacy and safety of a novel synergistic drug candidate, CRx-102, in hand osteoarthritis.
12/2007	Bone mineral density in patients with hand osteoarthritis compared to population controls and patients with rheumatoid arthritis.

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T K Kvien Research Topics

Disease

45	Rheumatoid Arthritis 01/2022 - 11/2000
16	Pain (Aches) 03/2017 - 10/2004
13	Necrosis 03/2016 - 01/2001
11	Fatigue 03/2017 - 12/2001
9	Psoriatic Arthritis 01/2022 - 09/2005
8	Osteoarthritis 01/2019 - 03/2003
8	Arthritis (Polyarthritis) 01/2010 - 04/2006
7	Inflammation (Inflammations) 04/2016 - 12/2002
6	Rheumatic Diseases (Rheumatism) 03/2016 - 09/2005
6	Osteoporosis 07/2009 - 10/2000
5	Joint Diseases (Joint Disease) 11/2021 - 09/2005
5	Ankylosing Spondylitis 11/2018 - 01/2011
3	Axial Spondyloarthritis 01/2022 - 01/2014
3	Disease Progression 04/2016 - 01/2001
3	Autoimmune Diseases (Autoimmune Disease) 09/2008 - 05/2005
2	Synovitis 04/2016 - 10/2009
2	Tenosynovitis 05/2011 - 10/2009
2	Myocardial Infarction 11/2010 - 11/2000
2	Injection Site Reaction 07/2009 - 10/2006
2	Acquired Immunodeficiency Syndrome (AIDS) 09/2008 - 04/2006
2	Headache (Headaches) 07/2008 - 10/2006
2	Nausea 10/2006 - 09/2001
2	Reactive Arthritis (Reiter Disease) 09/2004 - 03/2003
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2014
1	Ischemic Stroke 11/2010
1	Pharyngitis (Sore Throat) 07/2009
1	Laryngitis 07/2009
1	Vitiligo 03/2009
1	Arthralgia (Joint Pain) 07/2008
1	Hip Osteoarthritis (Coxarthrosis) 12/2007

Drug/Important Bio-Agent (IBA)

11	Antirheumatic Agents (DMARD)IBA 11/2021 - 09/2001
9	ametantrone (HAQ)IBA 03/2017 - 03/2000
6	Biological ProductsIBA 01/2022 - 08/2005
6	AntibodiesIBA 11/2021 - 12/2001
6	4-hexyloxyaniline (HOA)IBA 04/2016 - 12/2007
6	Tumor Necrosis Factor InhibitorsIBA 03/2016 - 01/2001
5	1- hydroxy- 5,8- bis(2- ((2- hydroxyethyl)amino)ethylamino)- 9,10- anthracenedioneIBA 01/2015 - 11/2005
5	Rheumatoid FactorIBA 05/2011 - 03/2000
5	Sulfasalazine (Azulfidine)FDA LinkGeneric 07/2009 - 01/2001
5	Methotrexate (Mexate)FDA LinkGeneric 07/2009 - 09/2005
5	Adrenal Cortex Hormones (Corticosteroids)IBA 08/2004 - 03/2000
4	C-Reactive ProteinIBA 11/2018 - 12/2009
4	Adalimumab (Humira)FDA Link 05/2011 - 10/2006
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2009 - 03/2003
4	Leflunomide (Arava)FDA LinkGeneric 11/2001 - 01/2001
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2009
3	Rituximab (Mabthera)FDA Link 01/2019 - 02/2007
3	LipidsIBA 08/2015 - 11/2010
3	CytokinesIBA 01/2015 - 03/2003
3	InterleukinsIBA 01/2015 - 03/2003
3	Anti-Citrullinated Protein AntibodiesIBA 02/2010 - 05/2008
3	Proteins (Proteins, Gene)FDA Link 01/2010 - 05/2008
2	Pharmaceutical PreparationsIBA 11/2021 - 07/2008
2	CholesterolIBA 08/2015 - 11/2010
2	LDL CholesterolIBA 08/2015 - 07/2015
2	OsteoprotegerinIBA 01/2015 - 11/2006
2	LigandsIBA 10/2012 - 11/2006
2	cyclic citrullinated peptideIBA 01/2010 - 02/2008
2	Leukocyte L1 Antigen Complex (Calgranulin)IBA 01/2010 - 05/2008
2	Etanercept (Enbrel)FDA Link 07/2009 - 10/2006
2	SteroidsIBA 07/2009 - 11/2000
2	Immunoglobulin G (IgG)IBA 02/2009 - 03/2008
2	Protein-Arginine DeiminasesIBA 02/2009 - 03/2008
2	Interleukin-10 (Interleukin 10)IBA 06/2008 - 03/2003
1	golimumab FDA Link 11/2021
1	secukinumabIBA 12/2018
1	BenzodiazepinesIBA 03/2017
1	Glucose (Dextrose)FDA LinkGeneric 01/2017
1	Choline (Choline Chloride)IBA 01/2017
1	cyclo(Arg-Pro) (CI 4)IBA 01/2017
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 08/2015
1	oxidized low density lipoproteinIBA 08/2015
1	Rosuvastatin Calcium (Crestor)FDA Link 07/2015
1	Cytokine Receptors (Cytokine Receptor)IBA 01/2015
1	Interleukin-17 (Interleukin 17)IBA 01/2015
1	Interleukin-23 (Interleukin 23)IBA 01/2015
1	CC ChemokinesIBA 10/2012
1	ApolipoproteinsIBA 11/2010
1	Triglycerides (Triacylglycerol)IBA 11/2010
1	VimentinIBA 02/2010
1	acetyl 4-aminosalicylic acidIBA 02/2010
1	Immunoglobulin M (IgM)IBA 01/2010
1	Immunoglobulin A (IgA)IBA 01/2010
1	Folic Acid (Vitamin M)FDA LinkGeneric 07/2009
1	Leucine-Rich Repeat ProteinsIBA 03/2009
1	EpitopesIBA 02/2009
1	ORALIT (ORS)IBA 01/2009
1	Fc Receptors (Fc Receptor)IBA 09/2008
1	prednisolone drug combination dipyridamoleIBA 07/2008
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 06/2008
1	Interleukin-4 (Interleukin 4)IBA 06/2008
1	Interleukin-1beta (Interleukin 1 beta)IBA 06/2008
1	AutoantibodiesIBA 06/2008
1	Viral AntibodiesIBA 06/2008
1	AntigensIBA 03/2008

Therapy/Procedure

14	Therapeutics 03/2016 - 11/2000
2	Operative Surgical Procedures 03/2011 - 10/2009
2	Physical Therapy Modalities (Physical Therapy Technique) 01/2008 - 10/2004
2	Exercise Therapy (Therapy, Exercise) 01/2008 - 10/2004
1	Perioperative Period 07/2009